Question Detail

BIO 101 BIO 101 Past Questions Objective Question

Question

In the transformation experiment to demonstrate that DNA is the hereditary material, mice were infected with
Options
A Heat- killed, smooth, pneumococcus bacteria mixed with live, smooth bacteria.
B Heat-killed, rough pneumococcus bacteria with live rough bacteria.
C live, smooth pneumococcus bacteria mixed with heat-killed rough bacteria.
D live rough pneumococcus bacteria mixed with heat-killed smooth bacteria.
Correct Answer
Correct Answer

Option D is the correct answer.

Detailed Explanation

In Griffith's experiment, he showed that something from heat-killed pathogenic (smooth) bacteria could transform live non-pathogenic (rough) bacteria into pathogenic ones. The key injection that killed the mice was the mixture of live rough (R) bacteria and heat-killed smooth (S) bacteria. The live R bacteria were transformed by genetic material from the dead S bacteria, becoming virulent S bacteria and killing the mouse.

Hint

Which mixture combined a harmless live strain with a deadly, but heat-killed, strain?

Question Info