Question Detail
Question
Which of these enzyme reactions is not irreversible in glycolysis?
Correct Answer
Option C is the correct answer.
Detailed Explanation
In glycolysis, three steps are considered irreversible under physiological conditions: those catalyzed by hexokinase/glucokinase, phosphofructokinase-1 (PFK-1), and pyruvate kinase. The reaction catalyzed by 3-phosphoglycerate kinase (which produces 3-phosphoglycerate and ATP) is reversible. Therefore, 3-phosphoglycerate kinase is not irreversible.
Hint
Which of these kinases catalyzes a reversible step in glycolysis?