Question Detail
Question
Colchicine is a chemical that stops chromatids from separating during mitosis. Which phase will the cell reach and then stop dividing? A. anaphase B. interphase C. metaphase D. telophase
Correct Answer
Option A is the correct answer.
Detailed Explanation
Colchicine works by interfering with microtubule polymerization, thus disrupting the spindle apparatus. Since the signal for chromatid separation (anaphase) depends on spindle function, the cell arrests in metaphase, unable to transition to anaphase because the chromatids cannot be pulled apart.
Hint
It stops the 'pulling apart' stage from starting.