Question Detail
Question
Down syndrome occurs mostly due to non-dysfunctional occur during M phase of the cell cycle. This is most Common when the mother is: A. Less than 17 years old B. More than 35 years old C. Having her first child D. Having delay in child bearing
Correct Answer
Option B is the correct answer.
Detailed Explanation
The risk of having a child with Down syndrome (trisomy 21) increases significantly with maternal age, particularly after the age of 35. This is due to an increased likelihood of nondisjunction during meiosis in older eggs.
Hint
Advanced maternal age is a key risk factor.