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ZOO 101 ZOO 101 Past Questions Objective Question

Question

Consider the following: 1. Malate. 2. Succinate 3. Fumarate What is the correct sequence of the above metabolites in citric acid cycle?
Options
A 1-2-3
B 2-1-3
C 3-2-1
D 2-3-1
Correct Answer
Correct Answer

Option D is the correct answer.

Detailed Explanation

The correct sequence in the citric acid (Krebs) cycle is: Succinate → Fumarate → Malate. Succinate is converted to fumarate by succinate dehydrogenase (producing FADH2), fumarate is hydrated to malate by fumarase, and malate is oxidized to oxaloacetate by malate dehydrogenase (producing NADH).

Hint

Trace the steps from succinate to malate in the Krebs cycle, noting the order of intermediates.

Question Info