Question Detail
Question
Consider the following: 1. Malate. 2. Succinate 3. Fumarate What is the correct sequence of the above metabolites in citric acid cycle?
Correct Answer
Option D is the correct answer.
Detailed Explanation
The correct sequence in the citric acid (Krebs) cycle is: Succinate → Fumarate → Malate. Succinate is converted to fumarate by succinate dehydrogenase (producing FADH2), fumarate is hydrated to malate by fumarase, and malate is oxidized to oxaloacetate by malate dehydrogenase (producing NADH).
Hint
Trace the steps from succinate to malate in the Krebs cycle, noting the order of intermediates.