Question Detail
Question
Consider the following statements: 1. Chymotrypsinogen is converted into chymotrypsin by trypsin 2. Cholecystokinin is secreted by stomach. 3. Pepsin acts on peptide linkage in which tyrosine and phenylalanine are involved. Which of the statements given above are correct?
Correct Answer
Option C is the correct answer.
Detailed Explanation
Statement 1 is correct: Chymotrypsinogen is converted to active chymotrypsin by the proteolytic action of trypsin. Statement 3 is correct: Pepsin preferentially cleaves peptide bonds involving aromatic amino acids like tyrosine and phenylalanine. Statement 2 is incorrect: Cholecystokinin (CCK) is secreted by the I cells of the duodenum and jejunum (small intestine), not by the stomach.
Hint
Review the activation cascade of pancreatic proteases and the sources of gastrointestinal hormones.