Question Detail

CHM 102 Carboxylic Acid Derivatives: Nomenclature, Synthesis, and Reactions Objective Question
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Question

Which of the following is an activated ester derivative used in peptide synthesis?
Options
A Methyl ester
B Ethyl ester
C N-Hydroxysuccinimide ester
Correct Answer
D t-Butyl ester
Correct Answer

Option C is the correct answer.

Detailed Explanation

N-Hydroxysuccinimide (NHS) esters are activated esters that react readily with amines to form amides, used in bioconjugation and peptide synthesis.

Hint

Good leaving group for amide bond formation.

Question Info

Course: CHM 102
Topic: Carboxylic Acid Derivatives: Nomenclature, Synthesis, and Reactions
Type: Objective
Difficulty: Not specified
Question 334 of 1999
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