Question Detail

CHM 102 Carboxylic Acid Derivatives: Nomenclature, Synthesis, and Reactions Objective Question
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Question

The conversion of a primary amide to a primary amine with one less carbon is called:
Options
A Hofmann rearrangement (Hofmann degradation)
Correct Answer
B Curtius rearrangement
C Lossen rearrangement
D Schmidt reaction
Correct Answer

Option A is the correct answer.

Detailed Explanation

Hofmann rearrangement: RCONH2 + Br2 + NaOH → RNH2 + CO2 + 2 HBr. The product is a primary amine with one fewer carbon.

Hint

Amide to amine with loss of CO2.

Question Info

Course: CHM 102
Topic: Carboxylic Acid Derivatives: Nomenclature, Synthesis, and Reactions
Type: Objective
Difficulty: Not specified
Question 342 of 1999
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