Question Detail

CHM 102 General Chemistry II: Properties and Reactions of Ethers Objective Question

Question

In the Williamson ether synthesis, which combination gives the best yield?
Options
A Tertiary alkoxide + tertiary alkyl halide
B Alkoxide + primary alkyl halide
Correct Answer
C Alkoxide + secondary alkyl halide
D Phenol + tertiary alkyl halide
Correct Answer

Option B is the correct answer.

Detailed Explanation

The Williamson synthesis works best with primary alkyl halides or methyl halides via SN2. Tertiary halides undergo elimination instead.

Hint

SN2 requires an unhindered halide.

Question Info