Question Detail

CHM 102 Isolation and Purification of Organic Compounds Objective Question
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Question

Which type of chromatography separates based on molecular size (sieving effect)?
Options
A Thin layer chromatography
B Ion exchange chromatography
C Size exclusion chromatography (gel filtration)
Correct Answer
D Paper chromatography
Correct Answer

Option C is the correct answer.

Detailed Explanation

Size exclusion chromatography (also called gel filtration) separates molecules based on their size and shape. Larger molecules elute first because they cannot enter the pores of the stationary phase.

Hint

Large molecules come out first.

Question Info

Course: CHM 102
Topic: Isolation and Purification of Organic Compounds
Type: Objective
Difficulty: Not specified
Question 545 of 1999
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