Question Detail

CHM 102 Practice Questions Objective Question

Question

Which of the following halides is most reactive in an E2 reaction with sodium methoxide?
Options
A (CH3)3CCH2I
B (CH3)2CHCHICH3
Correct Answer
C (CH3)2CHCH2Br
D (CH3)2CHCH2Cl
Correct Answer

Option B is the correct answer.

Detailed Explanation

E2 reactions are favored by more substituted alkyl halides that can form more stable alkenes. (CH3)2CHCHICH3 (2-iodopentane) is a secondary iodide that can form a disubstituted alkene, making it more reactive than primary halides. Iodide is also a good leaving group.

Hint

Which halide is more substituted and has a good leaving group?

Question Info