Question Detail
Question
Which of the following halides is most reactive in an E2 reaction with sodium methoxide?
Correct Answer
Option B is the correct answer.
Detailed Explanation
E2 reactions are favored by more substituted alkyl halides that can form more stable alkenes. (CH3)2CHCHICH3 (2-iodopentane) is a secondary iodide that can form a disubstituted alkene, making it more reactive than primary halides. Iodide is also a good leaving group.
Hint
Which halide is more substituted and has a good leaving group?