Question Detail

MIC 121 MCB 102 BACTERIA Objective Question

Question

How are bacterial ribosomes structurally different from eukaryotic ribosomes, and why is this difference significant?
Options
A Bacterial ribosomes are 80S, while eukaryotic are 70S; this allows for broader antibiotic targeting.
B Bacterial ribosomes are smaller (70S) and lighter than eukaryotic (80S); this difference is exploited by some antibiotics.
Correct Answer
C Bacterial ribosomes have a 60S large subunit, eukaryotic have a 50S; this affects their speed of translation.
D Bacterial ribosomes lack a small subunit, while eukaryotic ribosomes have both; this impacts protein folding.
Correct Answer

Option B is the correct answer.

Detailed Explanation

Page 45 notes, 'Bacterial ribosomes are 70S particles (comprising a 50S large subunit and 30S small subunit)' and 'The ribosomes of prokaryotic cells are smaller and lighter than their eukaryotic counterparts. Some types of antibiotics exploit this difference by targeting the prokaryotic form and selectively disrupting bacterial protein synthesis.'

Hint

The document specifies the 'S' values for bacterial ribosomes and mentions how this difference is relevant to medicine.

Question Info