Question Detail

BIO 201 Objective Question

Question

Spectrum bias in diagnostic research refers to which methodological issue?
Options
A Evaluating the test in a sample that does not reflect the full severity range of the clinical target population
Correct Answer
B Using light spectroscopy equipment that is improperly calibrated
C Failing to randomize participants into equal parallel arms
D Misclassifying reference standard results due to poor sample storage
Correct Answer

Option A is the correct answer.

Detailed Explanation

Spectrum bias arises when the study population features a different spectrum of disease severity or mild cases compared to the intended clinical population.

Hint

No hint available

Question Info