Question Detail

BIO 201 Objective Question
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Question

In diagnostic microarrays, what does a high signal intensity of a specific probe spot indicate?
Options
A A high abundance of complementary target nucleic acid sequence in the hybridized sample
Correct Answer
B Incomplete washing leading to non-specific background precipitation
C Degradation of probe oligonucleotides by endogenous nucleases
D Selective inhibition of target hybridization by buffer salts
Correct Answer

Option A is the correct answer.

Detailed Explanation

Fluorescence intensity on microarray spots correlates directly with the amount of complementary labeled sample DNA/RNA bound to the probe.

Hint

No hint available

Question Info

Course: BIO 201
Type: Objective
Difficulty: Not specified
Question 51 of 285
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