Question Detail

BIO 201 Objective Question

Question

In a diagnostic parallel design, how is spectrum bias mitigated during sample collection?
Options
A By recruiting a continuous, representative sample of patients across the full spectrum of mild, moderate, and severe disease presentation.
Correct Answer
B By restricting inclusion criteria strictly to advanced, severe clinical cases and healthy young controls.
C By performing assay readouts without calibrating the spectrophotometer.
D By applying serial confirmation tests exclusively to borderline assay readouts.
Correct Answer

Option A is the correct answer.

Detailed Explanation

Spectrum bias occurs if the test is evaluated only on extreme cases; sampling across the full disease spectrum ensures realistic validity.

Hint

No hint available

Question Info