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BIO 201 Objective Question
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Question

Why is a crossover design generally unsuitable for diagnostic accuracy studies involving permanent physiological markers?
Options
A Diagnostic statuses or cellular marker conditions cannot be 'washed out' to reset baseline status.
Correct Answer
B Crossover designs require double the sample size of parallel designs.
C Parallel designs cannot process qualitative binary diagnostic outcome data.
D Reference standards cannot be applied to crossover study cohorts.
Correct Answer

Option A is the correct answer.

Detailed Explanation

Unlike drug trials where washout periods clear treatments, stable disease states or biological markers remain fixed, making crossover designs inappropriate.

Hint

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Question Info

Course: BIO 201
Type: Objective
Difficulty: Not specified
Question 67 of 285
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