Question Detail

BIO 201 Objective Question

Question

In diagnostic validation, what is the 'Limit of Detection' (LoD) defined as in a parallel standard curve assay?
Options
A The lowest analyte concentration that can be reliably distinguished from analytical background noise with statistical confidence.
Correct Answer
B The maximum linear concentration range of standard curve calibrators.
C The optical saturation point of the photodetector sensor.
D The median concentration value observed across healthy patient samples.
Correct Answer

Option A is the correct answer.

Detailed Explanation

LoD represents the lowest true concentration of analyte that produces a signal statistically distinct from a blank sample.

Hint

No hint available

Question Info