Question Detail

BIO 201 Objective Question
Take CBT

Question

When designing a parallel comparative study for high-throughput diagnostic sequencing, what is the role of an 'internal standard' spike-in?
Options
A To monitor sample extraction, library preparation efficiency, and sequencing depth per sample run.
Correct Answer
B To bind selectively to human genomic DNA and halt polymerisation reactions.
C To replace the requirement for negative control wells on the sequencing flow cell.
D To increase the read length of target short-read sequences.
Correct Answer

Option A is the correct answer.

Detailed Explanation

Internal control spike-ins provide benchmark readouts to track operational efficiency and reagent functionality across parallel sample runs.

Hint

No hint available

Question Info

Course: BIO 201
Type: Objective
Difficulty: Not specified
Question 90 of 285
Previous Course Details Next