Question Detail

BIO 201 Objective Question

Question

What is the consequence of applying the 'AND rule' (serial rule) instead of the 'OR rule' (parallel rule) to two diagnostic tests?
Options
A Specificity increases while sensitivity decreases.
Correct Answer
B Sensitivity increases while specificity decreases.
C Both sensitivity and specificity increase simultaneously.
D Both positive predictive value and negative predictive value drop to zero.
Correct Answer

Option A is the correct answer.

Detailed Explanation

Requiring both tests to be positive (AND rule) tightens diagnostic criteria, which boosts specificity at the cost of missing true cases (lower sensitivity).

Hint

No hint available

Question Info