Question Detail

BIO 201 Objective Question

Question

In diagnostic parallel cohort studies, what is 'incorporation bias'?
Options
A An error occurring when the index test under evaluation is actually used as part of the criteria for the reference standard.
Correct Answer
B An error caused by using non-sterile pipette tips during sample processing.
C The bias introduced by incorporating healthy controls with extreme biological phenotypes.
D The statistical distortion caused by running samples in duplicate rather than triplicate.
Correct Answer

Option A is the correct answer.

Detailed Explanation

Incorporation bias invalidates accuracy metrics because the test being evaluated forms part of the final reference diagnosis, artificially inflating performance.

Hint

No hint available

Question Info