Question Detail

BIO 201 Objective Question

Question

In parallel tissue histopathology processing, what is the main purpose of formal fixation (e.g., neutral buffered formalin)?
Options
A To cross-link cellular proteins and preserve tissue architecture against autolysis and degradation.
Correct Answer
B To selectively solubilize cellular membranes for total DNA extraction.
C To stain cellular nuclei with dark blue hematoxylin dye.
D To digest background collagen matrix prior to antibody hybridization.
Correct Answer

Option A is the correct answer.

Detailed Explanation

Fixation immobilizes proteins and cellular structures, maintaining native morphology for accurate microscopic diagnostic evaluation.

Hint

No hint available

Question Info