Question Detail

BIO 201 Objective Question

Question

In a diagnostic parallel assay evaluation, what is meant by 'analytical specificity'?
Options
A The capability of an assay to exclusively detect the target analyte without cross-reacting with non-target substances.
Correct Answer
B The probability that a patient with a positive assay outcome actually has the targeted disease.
C The minimum concentration of analyte that produces a detectable instrument response.
D The percentage of healthy control subjects who test negative under field conditions.
Correct Answer

Option A is the correct answer.

Detailed Explanation

Analytical specificity measures molecular discrimination (lack of cross-reactivity), distinguishing it from clinical specificity (correctly identifying healthy patients).

Hint

No hint available

Question Info