Question Detail

BIO 201 Genetics 1 Objective Question

Question

What physiological complication can arise during pregnancy when an Rh-negative mother carries an Rh-positive fetus?
Options
A Maternal hypercoagulation causing fetal sickle crises
B Erythroblastosis fetalis (hemolytic disease of the newborn) due to maternal anti-Rh IgG antibodies attacking fetal RBCs
Correct Answer
C Complete failure of the fetal cardiovascular circulation due to ABO antigen mismatch
D Inherited maternal microcephaly in subsequent female offspring
Correct Answer

Option B is the correct answer.

Detailed Explanation

Sensitization of an Rh- mother by Rh+ fetal RBCs induces anti-Rh (anti-D) IgG antibodies, which can cross the placenta in subsequent Rh+ pregnancies and cause erythroblastosis fetalis.

Hint

No hint available

Question Info