Question Detail
Question
What happens to pyruvate before entering the Krebs cycle?
Correct Answer
Option A is the correct answer.
Detailed Explanation
Pyruvate, produced in the cytoplasm by glycolysis, is transported into the mitochondrial matrix. There, the pyruvate dehydrogenase complex catalyzes its oxidative decarboxylation, converting it to acetyl-CoA, which then enters the Krebs cycle.
Hint
It undergoes a linking step that produces NADH and CO2.