Question Detail
Question
What would be the effect of a single amino acid substitution in the active site of an enzyme?
Correct Answer
Option B is the correct answer.
Detailed Explanation
The active site's precise three-dimensional shape is crucial for binding the substrate. Changing even one amino acid in this region can distort the active site, preventing substrate binding or catalysis, potentially rendering the enzyme non-functional.
Hint
The active site is highly specific.