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CHM 102 Fundamentals of Amines: Nomenclature, Isomerism, and Synthesis Objective Question
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Question

What is the Hofmann elimination?
Options
A Oxidation of amines to nitro compounds
B Reduction of amides to amines
C Exhaustive methylation of an amine followed by elimination to form an alkene
Correct Answer
D Reaction of amines with nitrous acid
Correct Answer

Option C is the correct answer.

Detailed Explanation

Hofmann elimination converts an amine to an alkene via formation of a quaternary ammonium salt followed by treatment with base, giving the less substituted alkene (Hofmann product).

Hint

Elimination from quaternary ammonium hydroxide.

Question Info

Course: CHM 102
Topic: Fundamentals of Amines: Nomenclature, Isomerism, and Synthesis
Type: Objective
Difficulty: Not specified
Question 255 of 1999
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