Question Detail

CHM 102 Fundamentals of Amines: Nomenclature, Isomerism, and Synthesis Objective Question

Question

What is the product of Hofmann degradation (Hofmann rearrangement) of an amide?
Options
A Primary amine with one less carbon
Correct Answer
B Primary alcohol
C Carboxylic acid
D Secondary amine
Correct Answer

Option A is the correct answer.

Detailed Explanation

Hofmann degradation (Br2/NaOH) converts a primary amide (RCONH2) to a primary amine (RNH2) with loss of one carbon atom.

Hint

RCONH2 → RNH2 + CO2.

Question Info