Question Detail

BIO 201 Objective Question

Question

Which principle dictates that all participants in a parallel trial should be analyzed within the groups to which they were originally allocated, regardless of protocol deviations?
Options
A Intention-to-treat (ITT) principle
Correct Answer
B Per-protocol (PP) analysis
C As-treated analysis
D Subgroup stratification
Correct Answer

Option A is the correct answer.

Detailed Explanation

Intention-to-treat preserves the benefits of initial random allocation, minimizing selection bias and avoiding optimistic overestimation of efficacy.

Hint

No hint available

Question Info