Question Detail

BIO 201 Objective Question

Question

What is the consequence of selecting an overly stringent (high) threshold cutoff value for a continuous quantitative biomarker test?
Options
A Specificity increases while sensitivity decreases
Correct Answer
B Sensitivity increases while specificity decreases
C Both sensitivity and specificity increase to 100%
D Both sensitivity and specificity decrease to zero
Correct Answer

Option A is the correct answer.

Detailed Explanation

Raising the threshold cutoff means fewer subjects test positive overall; false positives decrease (higher specificity), but false negatives increase (lower sensitivity).

Hint

No hint available

Question Info