Question Detail

BIO 201 Objective Question
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Question

What effect does a very low disease prevalence have on the Positive Predictive Value (PPV) of a parallel diagnostic testing regimen?
Options
A PPV decreases because lower prevalence causes false positives to outnumber true positives.
Correct Answer
B PPV increases dramatically due to the high sensitivity of parallel testing.
C PPV remains unchanged because intrinsic test sensitivity and specificity are fixed parameters.
D PPV approaches 100% as the number of healthy controls increases.
Correct Answer

Option A is the correct answer.

Detailed Explanation

In low-prevalence populations, even high-sensitivity parallel panels yield a larger absolute number of false positives than true positives, lowering PPV.

Hint

No hint available

Question Info

Course: BIO 201
Type: Objective
Difficulty: Not specified
Question 76 of 285
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